Registration
Opening and Welcome
Eraldo Antonini Lecture David Jones, UC London
Book presentation: Storia della Biochimica in Italia, edited by SIB
1° Keynote Nazzareno Capitanio, University of Foggia
Welcome Cocktail (Villa Bordonaro)
1° Symposium: Cancer cell signaling and metabolic rewiring
Chairs: Domenica Scumaci (UniCz), Antonella D’Anneo (UniPa)
Speakers:
Olivier Feron, UC Louvain, Bruxelles, Belgium
"How the tumor microenvironment directs metabolic preferences toward glucose or lipid utilization in cancer: implications for therapy"
Paola Chiarugi, University of Firenze
"Metabolic determinants of prostate cancer metastatic organotropism"
Luca Scorrano, University of Padova
"Chemical biology approaches identify small molecules targeting mitochondrial ultrastructure in cancer"
(+ 2 short)
Coffee Break
2° Symposium: Molecular mechanisms underlying the redox control on biological functions
Chairs: Luigi Palmieri (UniBa), Giovanni Li Volti (UniCt)
Speakers:
Maria Ankarcrona, Karolinska Institutet, Stockholm, Sweden
"Targeting Mitochondrial dysfunction in Alzheimer Disease"
Marzia Perluigi, University La Sapienza, Rome
"Redox imbalance and metabolic defects in the brain of Down Syndrome: a synergistic path to Alzheimer Disease"
Lucia Longhitano, University of Catania
"Heme oxygenase-1 derived carbon monoxide reduces bone marrow fibrotic transformation in myelofibrosis microenvironment"
(+ 2 short)
Light lunch and Poster Exhibition
3° Symposium: Membrane compartmentalization: contacts, transporters and nanodomains
Chairs: Cesare Indiveri (UniCal), Chiricozzi Elena (UniMi)
Speakers:
Sonja Sucic, Medical University of Vienna
"Pharmacochaperoning of human SLC6 transporter disease variants"
Maria Letizia Trincavelli, University of Pisa
"Mitochondrial translocator protein (TSPO): a key modulator in neurodegenerative processes"
Vito Nicola De Pinto, University of Catania
"Voltage Dependent anion selective channel: from function to structure to function"
(+ 2 short)
Coffee Break
2° Keynote Mauro Maccarrone, University of L'Aquila
"New advances on the interaction between endocannabinoids and other bioactive lipids in neuroinflammation"
Gala Dinner (Palazzo Francavilla)
4° Symposium: Advances in protein structure and function
Chairs: Francesca Cutruzzolà (uniRoma1), Stefano Ricagno (UniMi)
Speakers:
Johannes Buchner, Technical University of Munich
"How molecular chaperones fold proteins"
Marina Mapelli, IEO di Milano
"Dissecting Wnt-dependent self-renewal by integrative structural biology"
Angelo Toto, University La Sapienza, Rome
"The binding and folding properties of the C-terminal SH3 of Grb2 in isolation and in a multidomain context."
(+ 2 short)
Coffee Break
5° Symposium: Bioactive molecules for human health: current status and future prospectives
Chairs: Stefania Iametti (UniMi), Silvana Hrelia (UniBo)
Speakers:
Csaba Szabo, Università di Friburgo, Svizzera
"Hydrogen cyanide, the latest member of the mammalian gasotransmitter family: posttranslational protein modifications and cellular bioenergetic regulation"
Luciana Mosca, Università La Sapienza, Roma
"Extra virgin olive oil polyphenols for healthy aging: from bench to bedside"
Mario Allegra, Università di Palermo
(+ 2 short)
6° Symposium: New Trends in Biotechnology: from biomolecules to applications
Chairs: Chiara Schiraldi (UniCampania), Mauro Magnani (UniUrb)
Speakers:
Felipe Lombo, University of Oviedo
"Genomic and metabolic engineering for the heterologous production of flavonoids in bacterial factories, and their antitumor and anti-inflammatory effects in animal models for colon cancer and ulcerative colitis"Sheila Sadeghi, University of Torino
"Mimicking tandem reactions of drug metabolising enzymes using a microfluidic platform"Mirco Dindo, University of Perugia
(+ 2 short)
Light lunch and Poster Exhibition
Prizes
SIB Assembly
Closing Remarks
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